Plant stem cells carve their own niche

Stem cells are the precursors of differentiated cells and are, thus, indispensable for growth and development in plants and animals. Stem cells from both types of organisms share the fundamental features of a capacity for self-renewal and an ability to generate differentiated cells. The maintenance of stem cells in both systems is dependent upon reciprocal signalling between stem cells and the specialized tissue microenvironment known as the niche, which provides intercellular signals for stem cell regulation. One significantly underexplored facet of plant stem cells is the nature of their intrinsic transcriptional programme. A potentially rich avenue for addressing this deficiency is to combine laser-assisted microdissection and genome-wide transcriptional profiling to unravel the molecular road map controlling plant stem cells and their niches.