Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2843442 | Journal of Thermal Biology | 2010 | 4 Pages |
Abstract
The protective effects of vitamin E (VE) against hyperthermia-induced damage in bovine mammary epithelial cells (BMEC) were studied. The structure of BMEC membrane was damaged by hyperthermia treatment. The VE (25 nmol/ml) efficiently increased cell viability and attenuated morphological damages in hyperthermia-treated BMEC. Compared with the control, VE significantly reduced lactate dehydrogenase leakage and malondialdehyde formation in hyperthermia-treated BMEC. Meanwhile, superoxide dismutase activity was increased significantly in the presence of VE. It is inferred that VE displayed cytoprotective effects on hyperthermia-induced damage in BMEC through increasing intracellular antioxidant levels and decreasing lipid peroxidation.
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Authors
Hong-Yun Liu, Ke Zhao, Miao-Miao Zhou, Cong Wang, Jun-An. Ye, Jian-Xin Liu,