Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2843519 | Journal of Thermal Biology | 2008 | 5 Pages |
I wanted to follow the correlation between level of basal metabolic rate (BMR) and maximum response to injection of noradrenaline (MMRNA) in two lines of laboratory mice subjected to divergent, artificial selection toward high BMR (HBMR) and low BMR (LBMR). HBMR animals had heavier visceral organs (heart, liver, kidney, intestine), but their regulatory NST (MMRNA–BMR) was lower and interscapular brown adipose tissue (IBAT) lighter than in LBMR mice. Obligatory part of nonshivering thermogenesis (NST) (in other words BMR) depended on visceral organ mass, whereas regulatory NST correlates with mass of IBAT. BMR was not correlated with total NST capacity, but phenotypic correlation between obligatory and regulatory NST was negative. This suggests possibility of substitution of obligatory NST to thermoregulation in a place of the regulatory NST. Then total thermoregulatory energy expenditures do not change.