Article ID Journal Published Year Pages File Type
2843757 Journal of Thermal Biology 2006 15 Pages PDF
Abstract

Experimental analysis of deep-body thermoreception in 1912 put forward the thesis of hypothalamic thermoregulation, whereas experiments in 1935 suggested, as an antithesis, distributed central nervous thermoreception. The high/low Q10 concept of hypothalamic thermoreception and the discovery of spinal deep-body thermoreception, both published first in 1963, raised thesis and antithesis to new levels. Common work of the respective proponents, Hammel and the author, disclosed inter-class differences in deep-body thermosensor distribution between mammals and birds in 1975. Subsequent research has established, as the synthesis, the current concept of deep-body temperature control by partially independent, multiple input–output-effector loops.

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