| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 36858 | Trends in Biotechnology | 2016 | 5 Pages |
Abstract
Modulation of the mammalian target of rapamycin (mTOR), the principal regulator of cellular homeostasis, underlies the biological effects of engineered nanoparticles, including regulation of cell death/survival and metabolic responses. Understanding the mechanisms and biological actions of nanoparticle-mediated mTOR modulation may help in developing safe and efficient nanotherapeutics to fight human disease.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Laura Hulea, Zoran Markovic, Ivan Topisirovic, Thomas Simmet, Vladimir Trajkovic,