Article ID Journal Published Year Pages File Type
4395854 Journal of Experimental Marine Biology and Ecology 2012 5 Pages PDF
Abstract
► DBT is an endocrine disruptor in zebrafish. ► In vivo, DBT exposure decreases zfCYP19a, zfERβ1 and FST mRNA in the gonads. ► In vitro, DBT exposure inhibits testosterone induced luciferase activity. ► In vitro, DBT exposure increases ethinylestradiol induced luciferase activity. ► DBT's MOA is complex and may be due to the metabolism of DBT to MBT.
Related Topics
Life Sciences Agricultural and Biological Sciences Aquatic Science
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