Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4496527 | Journal of Theoretical Biology | 2013 | 8 Pages |
Abstract
⺠We developed a mathematical approach to evaluate the efficacy of antibiotic agents. ⺠A unified pharmacokinetics/pharmacodynamics formalism for a whole antibiotics range. ⺠Association of the in vivo drug concentration with the in vitro drug effect. ⺠An introduction of the Hill-dependency concept for antibiotic classification. ⺠Reveal surprising drug performance for different regimens.
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Authors
Jun Li, Fahima Nekka,