Stochastic resonance in Hodgkin–Huxley neuron induced by unreliable synaptic transmission

We systematically investigate the stochastic dynamics of a single Hodgkin–Huxley neuron driven by stochastic excitatory and inhibitory input spikes via unreliable synapses in this paper. Based on the mean-filed theory, a novel intrinsic neuronal noise regulation mechanism stemming from unreliable synapses is presented. Our simulation results show that, under certain conditions, the stochastic resonance phenomenon is able to be induced by the unreliable synaptic transmission, which can be well explained by the theoretical prediction. To a certain degree, the results presented here provide insights into the functional roles of unreliable synapses in neural information processing.

► We investigate the stochastic dynamics of Hodgkin–Huxley neuron with unreliable synapses. ► Based on the mean-filed theory, theoretical analysis is presented. ► We show that stochastic resonance can be induced by the unreliable synaptic transmission.