| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4496901 | Journal of Theoretical Biology | 2011 | 9 Pages |
Abstract
⺠Loop5 in Eg5 projects from the protein adjacent to the nucleotide site. ⺠Loop5 modulates Eg5 function by unresolved mechanisms. ⺠Spectroscopy has suggested that loop5 may interact with the nucleotide site. ⺠MD simulations are used to quantitatively test the interaction hypothesis. ⺠Simulations show loop5 can interact extensively with the nucleotide site.
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Authors
Timothy D. Harrington, Nariman Naber, Adam G. Larson, Roger Cooke, Sarah E. Rice, Edward Pate,