New stochastic carcinogenesis model with covariates: An approach involving intracellular barrier mechanisms

► New cancer model connects age-specific hazard rates with intracellular processes. ► New multiple-pathway model of carcinogenesis is based on lab tests/measurements. ► Analytical solution for the new carcinogenesis model is available. ► Barrier breaking mechanism model describes decline in cancer risk at advanced ages. ► New model of carcinogenesis shows strong predictive power.