Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4500323 | Mathematical Biosciences | 2012 | 6 Pages |
Abstract
⺠A mathematical model of ERK cyclic pathway including its substrate is proposed. ⺠Conditions for substrate-mediated modulation of ERK is mathematically derived. ⺠A more detailed model with biologically relevant parameter values is examined. ⺠Possible mechanisms for the substrate control of ERK signal are suggested.
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Authors
Tsuyoshi Hirashima,