Article ID Journal Published Year Pages File Type
4500762 Mathematical Biosciences 2008 10 Pages PDF
Abstract

For a single patch SIRS   model with a period of immunity of fixed length, recruitment-death demographics, disease related deaths and mass action incidence, the basic reproduction number R0R0 is identified. It is shown that the disease-free equilibrium is globally asymptotically stable if R0<1R0<1. For R0>1R0>1, local stability of the endemic equilibrium and Hopf bifurcation analysis about this equilibrium are carried out. Moreover, a practical numerical approach to locate the bifurcation values for a characteristic equation with delay-dependent coefficients is provided. For a two patch SIRS model with travel, it is shown that there are several threshold quantities determining its dynamic behavior and that travel can reduce oscillations in both patches; travel may enhance oscillations in both patches; or travel can switch oscillations from one patch to another.

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