Article ID Journal Published Year Pages File Type
4502613 Theoretical Population Biology 2008 7 Pages PDF
Abstract

It is well known that the neutral allelic frequency spectrum of a population is affected by the history of population size. A number of authors have used this fact to infer history given observed allele frequency data. We ask whether perfect information concerning the spectrum allows precise recovery of the history, and with an explicit example show that the answer is in the negative. This implies some limitations on how informative allelic spectra can be.

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Life Sciences Agricultural and Biological Sciences Agricultural and Biological Sciences (General)
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