| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4508240 | Current Opinion in Insect Science | 2015 | 9 Pages |
•Sites of virus attachment and entry in the vector offer key sites for disruption of transmission.•Viral capsid protein fused to a toxin is a promising vector control strategy.•Transgenic expression of viral proteins in plants can block virus acquisition and transmission.•RNA interference has potential for disruption of virus transmission and elimination of the vector.•Proteomic tools can be used to identify candidate vector proteins that function in virus transmission.
Plant-infecting viruses are transmitted by a diverse array of organisms including insects, mites, nematodes, fungi, and plasmodiophorids. Virus interactions with these vectors are diverse, but there are some commonalities. Generally the infection cycle begins with the vector encountering the virus in the plant and the virus is acquired by the vector. The virus must then persist in or on the vector long enough for the virus to be transported to a new host and delivered into the plant cell. Plant viruses rely on their vectors for breaching the plant cell wall to be delivered directly into the cytosol. In most cases, viral capsid or membrane glycoproteins are the specific viral proteins that are required for transmission and determinants of vector specificity. Specific molecules in vectors also interact with the virus and while there are few-identified to no-identified receptors, candidate recognition molecules are being further explored in these systems. Due to the specificity of virus transmission by vectors, there are defined steps that represent good targets for interdiction strategies to disrupt the disease cycle. This review focuses on new technologies that aim to disrupt the virus–vector interaction and focuses on a few of the well-characterized virus–vector interactions in the field. In closing, we discuss the importance of integration of these technologies with current methods for plant virus disease control.
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