| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4512438 | Industrial Crops and Products | 2016 | 4 Pages |
•Antibacterial activity of cinnamon oil on resistant microorganisms was determined.•The microorganisms were carbapenem resistant nosocomial A.baumannii and P. aeruginosa.•Composition of essential oil was analysed by GC/MS.•Cinnamon oil can be a potential candidate for new bioactive agents.
Widespread existence of drug-resistant pathogens poses a threat to the successful treatment of bacterial diseases and increases the need for new antibacterial agents. Natural products are the basic source of antibacterial therapeutic agents for now, and will remain so in the future. Therefore, the aim of this study was to determine the antibacterial activity of cinnamon oil against carbapenem-resistant nosocomial isolates of Acinetobacter baumannii (111) and Pseudomonas aeruginosa (136). The essential oil composition of cinnamon oil was analyzed by GC, GC/MS and the antimicrobial effect of cinnamon oil was determined by disk diffusion method. The observed zone diameters were compared with carbapenem breakpoints (CLSI standard) and it was found that only one of the P. aeruginosa isolates was within resistance limits. Thus, cinnamon oil has antimicrobial activity with potential use as an antimicrobial agent in the pharmaceutical industry and an additive in the food industry.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
