Biosynthesis, characterization and antibacterial effect of plant-mediated silver nanoparticles using Ceropegia thwaitesii – An endemic species

•The synthesis of plant based nanoparticles which are simple, cost effective and ecofriendly.•The synthesized nanoparticles were analyzed by FTIR, XRD, SEM and EDS.•Inhibitory activity of AgNPs was tested against human pathogens showed high response.•The outcome of this paper will be useful for further research in the silver nanoparticles in the health care and cosmetic industries.

Leaf extract of in vitro raised plants of Ceropegia thwaitesii was assessed for the green synthesis of silver nanoparticles (AgNPs). The biosynthesized AgNPs were authorized by UV–vis spectrophotometer with surface plasmon resonance at 430 nm. The scanning electron microscope (SEM), dynamic light scattering (DLS) analysis confirmed the particle size 100 nm, and X-ray diffraction (XRD) confirmed the crystalline character of AgNPs. Further, Fourier transform infrared (FTIR) authorized the presence of triterpenoids and methoxy groups played an important reduction role in the synthesis process. It shows the significant antibacterial efficacy against Salmonella typhi, Shigella flexneri, Klbsiella pneumonia, Eschericia coli and others species. From the results, it is suggested that green synthesized AgNPs could be used effectively in future biomedical engineering.

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