| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4520268 | South African Journal of Botany | 2016 | 5 Pages |
•This is the first report comprising in vitro photoprotective and antioxidant activities of dried roots of western Himalayan plant Potentilla atrosanguinea•One noval compound methyl pentatetraconta-30,32,34,36,38,40,42-heptaenoate (PA-1) and pentadecylbutyrate (PA-2) was isolated by column chromatography.•It can be used as photo protective agents in sunscreen preparation in pharmaceutical industry as well as can be considered as a natural source of antioxidants.
In vitro photoprotective and antioxidant activities of dried aqueous-methanolic (H2O/MeOH) crude extract and ethyl acetate (EtOAc), n-butanol (n-BuOH) as well as aqueous (H2O) fractions of roots of western Himalayan plant Potentilla atrosanguinea (Himalayan cinquefoil) were evaluated. The ability of protection against UVB region followed the trend EtOAc > n-BuOH > H2O/MeOH > H2O. Total phenol content of crude H2O/MeOH extract was found to be 429.808 mg GAE/g. The H2O/MeOH crude extract showed highest antioxidant of DPPH radical scavenging, superoxide anion radical scavenging and cupric ion reducing of 90.04, 78.86 and 88.64% respectively at 200 μg/mL. One new compound methyl pentatetraconta-30,32,34,36,38,40,42-heptaenoate (PA-1) along with a known pentadecylbutyrate (PA-2) was isolated by column chromatography. Results indicated the importance of root extracts as photoprotective agents in sunscreen preparation in the pharmaceutical industry and considered as a natural source of antioxidants.
