| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4521824 | South African Journal of Botany | 2007 | 4 Pages |
Abstract
Mentha aquatica L. is used in Zulu traditional medicine for spiritual purposes and an ethanolic leaf extract has previously shown strong affinity to the GABA-benzodiazepine receptor. Viridiflorol from the essential oil and (S)-naringenin from an ethanolic extract was isolated by bioassay-guided fractionation using binding to the GABA-benzodiazepine site. Viridiflorol had an IC50 of 0.19 M and (S)-naringenin of 0.0026 M.
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Authors
A.K. Jäger, J.P. Almqvist, S.A.K. Vangsøe, G.I. Stafford, A. Adsersen, J. Van Staden,