Effects of a toxic cyanobacterial bloom (Planktothrix agardhii) on fish: Insights from histopathological and quantitative proteomic assessments following the oral exposure of medaka fish (Oryzias latipes)

► Medaka are used to assess the toxic effect of the cyanobacteria Planktothrix agardhii. ► Anatomo-pathological effects and immunolocalisation of micocystins were analyzed on liver. ► Deregulation of 15 proteins involved in lipid metabolism, cellular redox balance, and cytoskeletal organisation. ► Vitellogenin induced by the cyanobacterial extract in the liver of juvenile medaka. ► Potential endocrine disrupting effect of the cyanobacterial bloom extract.