| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4529812 | Aquatic Toxicology | 2011 | 13 Pages |
Abstract
⺠We constructed subtractive cDNA libraries between worms exposed to BaP and control. ⺠A total of 2422 new high quality ESTs were obtained in the subtracted cDNA libraries. ⺠Annotation of ESTs suggested complex toxicological responses to BaP in worms. ⺠Expression levels of 50 marker genes illustrated the representative toxic effects. ⺠Results show that the polychaete P. nuntia has a set of inducible tumor-related genes.
Keywords
RT-Q-PCRPAHPDCD10Programmed cell death 10CyPCDCPerinereis nuntiablastxPolychaeteSSHBAPDMSOROSBLAST, basic local alignment search toolESTBenzo[a]pyreneMolecular functionExpressed Sequence Tagcellular componentKEGG یا Kyoto Encyclopedia of Genes and Genomes Kyoto Encyclopedia of Genes and GenomesDimethyl sulfoxideCarcinogenCytochrome P450biological processMafKGene ontologySuppression subtractive hybridizationPolycyclic aromatic hydrocarbonReactive oxygen species
Related Topics
Life Sciences
Agricultural and Biological Sciences
Aquatic Science
![Toxicity evaluation of benzo[a]pyrene on the polychaete Perinereis nuntia using subtractive cDNA libraries](/preview/png/4529812.png "First Page Preview: Toxicity evaluation of benzo[a]pyrene on the polychaete Perinereis nuntia using subtractive cDNA libraries")
Authors
Senlin Zheng, Xiaoyan Qiu, Bin Chen, Xingguang Yu, Kangli Lin, Mei Bian, Zhenghua Liu, Hao Huang, Weiwei Yu,