Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5151111 | Inorganic Chemistry Communications | 2017 | 12 Pages |
Abstract
Two new organometallic compounds were synthesized in this study, namely, [Ru(η6-anethole)(en)(X)]PF6, where X = Br (5) or I (6), in order to assess the effect of different leaving groups on the biological activity of the Ru(η6-anethole)(en) scaffold. Compound 6 exhibited some selectivity (3-fold) between the human colon tumor (HT-29) and human colon non-tumor (CCD-841) cell lines that make this compound suitable for further drug development studies.109
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
David Astudillo, Antonio Galdámez, Maritza E. Sanguinetti, Joan Villena, Franz A. Thomet,