Synthesis, characterization, in vitro SAR and in vivo evaluation of N,Nâ²bisnaphthylmethyl 2-alkyl substituted imidazolium salts against NSCLC

Article ID	Journal	Published Year	Pages	File Type
5155469	Bioorganic & Medicinal Chemistry Letters	2017	12 Pages	PDF

Keywords

FDA DTP NCI IC50 2-hydroxypropyl-β-cyclodextrin 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide Ct-DNA Calf thymus DNA MTT intraperitoneal FID Food and Drug Administration Lung cancer NSCLC Non-small cell lung cancer Cyclodextrin Anti-tumor Anti-cancer Inhibitory Concentration 50%Phosphatidylserine National Cancer Institute Imidazolium salt Propidium iodide

Related Topics

Physical Sciences and Engineering Chemistry Organic Chemistry

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Synthesis, characterization, in vitro SAR and in vivo evaluation of N,Nâ²bisnaphthylmethyl 2-alkyl substituted imidazolium salts against NSCLC

Authors

Michael A. DeBord, Marie R. Southerland, Patrick O. Wagers, Kristin M. Tiemann, Nikki K. Robishaw, Kyle T. Whiddon, Michael C. Konopka, Claire A. Tessier, Leah P. Shriver, Sailaja Paruchuri, David A. Hunstad, Matthew J. Panzner, Wiley J. Youngs,