Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5519028 | Reproductive Biology | 2017 | 5 Pages |
Abstract
The aim of this study was to determine how 60-min ischemia changes the expression of hypoxia inducible factor 1α (HIF-1α) and superoxide dismutases (SOD)-1 and â2 in selected regions of porcine uterine horns. The results showed that 60-min ischemia of the porcine uterus conducted at the mid-secretory estrous phase caused decreased HIF-1α and increased SOD-2 gene expression. Higher expression of SOD-2 suggests that this enzyme may play an important role in the suppression of HIF-1α accumulation in an ischemic endometrium.
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Authors
Joanna Kwiatkowska, Barbara WÄ
sowska, PrzemysÅaw Gilun,