| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5522615 | Stem Cell Research | 2017 | 5 Pages |
Abstract
We describe the generation of a biallelic GBA deletion human embryonic stem cell line using zinc finger nuclease-mediated gene targeting. The homozygous targeting of exon 4 of the GBA locus leads to a complete loss of glucocerebrosidase (GCase) protein expression.
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