Evaluation of the efficacy of the Japanese rabies RC-HL strain vaccine in domestic dogs using past and present data: Prediction based on logistic regression and meta-analysis

Therefore, the yearly booster requirement of the current mandatory vaccination policy in Japan is reasonable in terms of its frequency. However, there is potential for future policy amendment to one that requires less frequent boosters, i.e. a booster is required within one year after primary vaccination and then every two to three years.