Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5544722 | Veterinary Immunology and Immunopathology | 2017 | 15 Pages |
Abstract
These results confirm that CD45 protein is lacking on cell surface irrespective of the technique and antibody source adopted. This phenotypic aberrancy is apparently due to the absence of gene transcription, as CD45 DNA was present, whereas CD45 transcript was virtually absent in the neoplastic cells. The data here reported support further studies investigating possible factors impairing CD45 gene transcription.
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Authors
V. Martini, M. Cozzi, A. Aricò, G. Dalla Rovere, A. Poggi, F. Albonico, M. Mortarino, E. Ciusani, L. Aresu, S. Comazzi,