| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5545021 | The Veterinary Journal | 2017 | 7 Pages |
Abstract
Transient excretion of CPV DNA was detected in 2.0% of dogs before vaccination. About one quarter of dogs (23.0%) shed CPV DNA during the post-vaccination period, but field and vaccine virus differentiation by VP2 gene sequencing was only successful in few samples. Faecal CPV excretion occurred despite protective serum antibody titres. Post-vaccination CPV shedding was not related to adequate antibody response after vaccination or to the occurrence of gastrointestinal side-effects. Despite individual differences, CPV DNA was detectable for up to 28 days after vaccination, although the faecal CPV DNA load in these clinically healthy dogs was very low.
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Authors
M. Freisl, S. Speck, U. Truyen, S. Reese, A.-L. Proksch, K. Hartmann,