Article ID Journal Published Year Pages File Type
5590421 Infection, Genetics and Evolution 2017 7 Pages PDF
Abstract
The experimental and in silico results matched very well and led us to propose a pst2 promoter sequence upstream of pstS gene distinct from the previously annotated. Furthermore, V. cholerae O1 pst2 operon transcription is PhoB-dependent and generates a polycistronic mRNA molecule that is rapidly processed into minor transcripts of distinct stabilities. The most stable was the pstS-encoding mRNA, which correlates with PstS higher levels relative to other Pst2 components in Pi-starved cells. The relatively higher stability of pstS and pstB transcripts seems to rely on the secondary structures at their 3′ untranslated regions that are known to block 3′-5′ exonucleolytic attacks.
Related Topics
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