Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5803077 | Veterinary Parasitology | 2014 | 11 Pages |
â¢Relationships between haematological parameters and sheep nematode resistance were defined.â¢A blood based test for identification of nematode resistant sheep was developed.â¢The test can be applied in a single blood sample and without knowledge of infection status.â¢The algorithms classify susceptible sheep with 80-100% accuracy.
Gastrointestinal nematodes remain a major limitation to the productivity of livestock systems. Selective breeding to produce populations that have an enhanced ability to resist infection is a viable and ongoing option to reduce this impact. The development of new phenotypes that facilitate this process is therefore of great interest. For this reason we explored relationships between haematological parameters and the ability of sheep to resist nematode infection. A multivariate analytical approach was used to define algorithms based on the blood parameters that can be used to rank the ability of sheep to resist nematode infection in a single blood sample and can be applied independent of infection status. The algorithms were shown to classify susceptible sheep with a 100% accuracy and resistant sheep with 80% accuracy. Further development of this platform approach may be an important advance for small ruminant production systems worldwide and might also be applied to other diseases of livestock or even environmental stressors such as heat.