| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5817156 | Experimental and Toxicologic Pathology | 2014 | 6 Pages |
Abstract
Our results suggest that growth stimulus induced by the use of PL did not significantly increase micronucleus formation in CHO-K1 cells compared to negative control. Micronucleus testing in conjunction with HCS could represent a valid tool to evaluate the safety of ancillary materials used in the production of cell-based medicinal products.
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Authors
Martina Bernardi, Valentina Adami, Elena Albiero, Domenico Madeo, Francesco Rodeghiero, Giuseppe Astori,