| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5908178 | Infection, Genetics and Evolution | 2016 | 5 Pages |
â¢Genetic relationship between lung and liver localization of hydatid cysts.â¢The genetic differentiation was due to the host species and the cyst localization.â¢The lung and liver isolates from G1 genotype were clearly different.â¢There are two specialized populations that are more or less successful according to host susceptibility.
G1 genotype of Echinococcus granulosus sensu stricto is the major cause of hydatidosis in Northern Africa, Tunisia included. The genetic relationship between lung and liver localization were studied in ovine, bovine and human hydatid cysts in Tunisia. Allozyme variation and single strand conformation polymorphism were used for genetic differentiation. The first cause of genetic differentiation was the host species and the second was the localization (lung or liver). The reticulated genetic relationship between the liver or the lung human isolates and isolates from bovine lung, is indicative of recombination (sexual reproduction) or lateral genetic transfer. The idea of two specialized populations (one for the lung one for the liver) that are more or less successful according to host susceptibility is thus proposed.
