Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5909617 | Infection, Genetics and Evolution | 2014 | 7 Pages |
Abstract
Our data indicates that GII.4 continues to be the predominant NoV genotype circulating in the Finnish community, and the changes in the P2 domain over time result in the development of new variants that cause AGE in children. Future NoV vaccines should either induce type specific immunity for each variant or, alternatively, induce broadly reactive protective immunity covering multiple variants.
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Authors
Leena Huhti, Vesna Blazevic, Leena Puustinen, Maria Hemming, Marjo Salminen, Timo Vesikari,