| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5910191 | Infection, Genetics and Evolution | 2014 | 5 Pages |
Abstract
In North African subjects, the PNPLA3 I148M variant apparently stimulates liver cancer development without interfering on the HCV clearance process. This polymorphism may, therefore, represent a valuable genetic marker to monitor liver cancer risk in populations from the Southern bank of the Mediterranean.
Keywords
NAFLDSVRRVBqRT-PCRPegIFN-αALTPNPLA3MCHCHBsAgCHCPBMCsHCCASTAspartate aminotransferaseAlanine aminotransferaseHepatitis B surface antigenNonalcoholic fatty liver diseasetriglycerideRibavirinperipheral blood mononuclear cellsAnti-HCVGenetic markerchronic hepatitis CHepatitis C virusHCVQuantitative reverse transcriptase-polymerase chain reactionsustained virological responseSpontaneous clearanceHepatocellular carcinoma
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Authors
Sayeh Ezzikouri, Rhimou Alaoui, Sana Tazi, Salwa Nadir, Naima Elmdaghri, Pascal Pineau, Soumaya Benjelloun,