Comparative genomics of oral isolates of Streptococcus mutans by in silico genome subtraction does not reveal accessory DNA associated with severe early childhood caries

Article ID	Journal	Published Year	Pages	File Type
5910216	Infection, Genetics and Evolution	2014	10 Pages	PDF

Abstract

Our results suggest that S. mutans strains derived from caries active or caries free dentitions cannot be differentiated based on the presence or absence of specific genetic elements. Our in silico genome subtraction method is available as the Microbial Genome Comparison (MGC) tool, with a user-friendly JAVA graphical interface.

Keywords

CDF UPGMA ORFs PCoA Severe early childhood caries Streptococcus mutans Principal Coordinate Analysis unweighted pair group method with arithmetic mean Software Virulence Pathogenesis Dental caries Comparative genomics

Related Topics

Life Sciences Agricultural and Biological Sciences Ecology, Evolution, Behavior and Systematics

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Comparative genomics of oral isolates of Streptococcus mutans by in silico genome subtraction does not reveal accessory DNA associated with severe early childhood caries

Authors

Argimón Silvia, Konganti Kranti, Chen Hao, Alexander V. Alekseyenko, Brown Stuart, Page W. Caufield,