| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5910426 | Infection, Genetics and Evolution | 2012 | 7 Pages |
Abstract
⺠This study provides with a first insight on Mycobacterium tuberculosis complex epidemiology and genetic diversity in the Cross River State, Nigeria. ⺠Majority of the clustered isolates were phylogeographically specific of West Africa; 52% belonged to the LAM10-CAM (Cameroon lineage) of M. tuberculosis, and 33% to the AFRI_2 sublineage of M. africanum. ⺠Apparently the proportion of evolutionary ancestral M. africanum is gradually decreasing in West-Africa. These strains are being replaced by more successful, evolutionary recent M. tuberculosis, particularly the LAM10-CAM lineage; a significant proportion (10%) was concomittantly multidrug-resistant in this study.
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Authors
Benjamin P. Thumamo, Anne E. Asuquo, Lydia N. Abia-Bassey, Lovett Lawson, Véronique Hill, Thierry Zozio, Nnamdi Emenyonu, Francis O. Eko, Nalin Rastogi,