| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5910512 | Infection, Genetics and Evolution | 2013 | 9 Pages |
Abstract
⺠We compared HIV-1 Gag subtype A sequences from two immune-genetically diverged populations, namely, Kenyan and Pakistani. ⺠Certain mutations unique to either Pakistani or Kenyan samples were found to alter the epitope pattern in these study groups. ⺠Unique selection pressures can steer the direction of viral epitope evolution in the host populations. ⺠Population-specific HIV epitopes have to be taken into account while designing vaccines for HIV.
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Authors
Syed H. Abidi, Aniqa Shahid, Laila S. Lakhani, Muhammad R. Khanani, Peter Ojwang, Nancy Okinda, Reena Shah, Farhat Abbas, Sarah Rowland-Jones, Syed Ali,