| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5910944 | Infection, Genetics and Evolution | 2013 | 8 Pages |
Abstract
⺠SNPs in pfmdr1/pfmrp1 was examined in P. falciparum after 4 years of introducing SP-artesunate in Iran. ⺠pfmdr1 86Y (46%) and 184F (2%) mutations were detected in the examined samples. ⺠In pfmrp1 gene, 191Y (76.5%), 437A (69.5%), 876V (64.5%) and 1390I (17%) mutations were detected. ⺠All isolates harbored a single copy of the Pfmdr1 gene. ⺠No mutations associated with ACT resistance significantly changed 4 years after adoption of ACT in Iran.
Related Topics
Life Sciences
Agricultural and Biological Sciences
Ecology, Evolution, Behavior and Systematics
Authors
Sakineh Pirahmadi, Sedigheh Zakeri, Mandana Afsharpad, Navid Dinparast Djadid,