| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5911036 | Infection, Genetics and Evolution | 2013 | 4 Pages |
In this study, using multilocus microsatellite analysis, we report the genetic characterization of 27 Candida parapsilosis isolates recovered in two different periods of time (2007-2009 and 2011-2012) from infants hospitalized in the neonatal intensive care unit of a hospital in Messina, Italy. The results revealed the persistence and dominance of a particular infectious genotype among NICU patients and highlight the power of the used microsatellite markers in clarifying epidemiologic associations, detect micro-evolutionary variations and facilitating the recognition of outbreaks.
⺠We studied Candida parapsilosis isolates mainly recovered from blood cultures of infants. ⺠No Candida orthopsilosis or Candida metapsilosis were found in this study. ⺠Multilocus microsatellite analysis revealed a cluster of highly related genotypes. ⺠The study shows persistence and possible cross-transmission of a particular infectious genotype. ⺠Microsatellite markers used are suitable in clarifying epidemiologic associations.
