| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5911233 | Infection, Genetics and Evolution | 2012 | 9 Pages |
Abstract
⺠Polymorphism at FLI1 was shown by us to important in Leishmania braziliensis infection. ⺠FLI1 interacts with CTGF, FLII, and TGFB pathway genes in wound healing. ⺠We find association with CTGF, TGFBR2, SMAD2, SMAD7 for cutaneous disease. ⺠We find association with SMAD3 and SMAD7 for mucocutaneous disease. ⺠Wound healing genes are important determinants of cutaneous leishmaniasis.
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Authors
Léa Castellucci, Sarra E. Jamieson, Lucas Almeida, Joyce Oliveira, Luiz Henrique Guimarães, Marcus Lessa, Michaela Fakiola, Amélia Ribeiro de Jesus, E. Nancy Miller, Edgar M. Carvalho, Jenefer M. Blackwell,