| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5911278 | Infection, Genetics and Evolution | 2012 | 5 Pages |
Molecular genetic and antigenic features of influenza A/H3N2 virus strains isolated in Western Siberia in 2011 are similar to those of the vaccine strain A/Perth/16/2009 despite a number of unique amino-acid changes. The strains lack specific amino-acid changes in NA protein providing decrease of sensibility to NA inhibitors activity that used in medical practice. Based on phylogenic analysis of HA protein amino-acid sequences examined strains are similar to influenza A/H3N2 virus strains circulating at the moment in Eurasia.
⺠H3N2 virus strains circulating in 2009-2011 in Western Siberia were described. ⺠HA of strains of 2011 are similar to HA of A/Victoria/210/2009 and A/Hessen/5/2010. ⺠HA of strains of 2011 belong to 1 of 2 phylogenetic groups from A/Perth/16/2009 clade. ⺠Strains do not contain specific amino-acid changes in NA protein causing reduction of sensitivity to NA inhibitors.
