Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5911572 | Infection, Genetics and Evolution | 2011 | 10 Pages |
Abstract
⺠Human keratinocytes are target cells for DENV. ⺠Infection of keratinocytes by DENV up regulates the expression of antiviral type 1 interferon related genes. ⺠Expression of anti-microbial genes is modulated during DENV infection of human keratinocytes.
Keywords
NF-κBretinoic acid inducible gene-IWNVRIG-IRNaseIRFRLIPRRsPKRDENVMyeloid differentiation primary response protein 88TLRMDDCsRNase LRNase L InhibitorhpiHbdMYD882′,5′-oligoadenylate synthetaseISGsMOIInnate immunityinterferonIFNToll-like receptorribonucleasehours post infectionDendritic cellsLangerhans cellsinterferon regulatory factornuclear factor κBOASDengue virusWest Nile virusmultiplicity of infectionInterferon-stimulated genesKeratinocytepattern recognition receptors
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Authors
Pornapat Surasombatpattana, Rodolphe Hamel, Sirilaksana Patramool, Natthanej Luplertlop, Frédéric Thomas, Philippe Desprès, Laurence Briant, Hans Yssel, Dorothée Missé,