Article ID Journal Published Year Pages File Type
5911894 Infection, Genetics and Evolution 2011 6 Pages PDF
Abstract
▶ Population-level polymorphism in eight coding genes of HIV-1 subtype B. ▶ Evidence of both past and ongoing purifying selection. ▶ Evolutionary conflict between immune escape and functional constraint. ▶ Amino acid sequences of CD4 epitopes subject to strong functional constraint.
Keywords
Related Topics
Life Sciences Agricultural and Biological Sciences Ecology, Evolution, Behavior and Systematics
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Conflicting selection pressures on T-cell epitopes in HIV-1 subtype B
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