Phylogenetic analysis of four nuclear protein-encoding genes largely corroborates the traditional classification of Bivalvia (Mollusca)

► We resolved basal relationships of bivalve mollusks using four protein-encoding genes. ► We recovered monophyly of all major bivalve subclasses and higher taxonomic ranks, including Autobranchia and Heteroconchia. ► We evaluated phylogenetic signal obtained using nuclear ribosomal versus mitochondrial versus nuclear protein-encoding genes.