| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5920484 | Molecular Phylogenetics and Evolution | 2011 | 19 Pages |
Abstract
⺠A structure-based alignment of DHFR from 22 species was performed. ⺠A metric for the degree of conservation at each site in the alignment was generated. ⺠Differences were identified in active site and non-active site residue sequence variability. ⺠The phylogenetic tree generated from the alignment was comparable to the canonical one.
Related Topics
Life Sciences
Agricultural and Biological Sciences
Ecology, Evolution, Behavior and Systematics
Authors
David Hecht, Jonathan Tran, Gary B. Fogel,