| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6370892 | Journal of Theoretical Biology | 2013 | 10 Pages |
Abstract
⺠First ever mathematical model of colitis-associated colon cancer. ⺠Multiscale approach connecting genes mutations to epithelium proliferation. ⺠TP53 mutation and inflammed colonic mucosa contribute to cancer early development. ⺠TP53 mutations play a primary role, followed by APC mutation.
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Authors
Wing-Cheong Lo, Edward W. Jr., Charles L. Hitchcock, Avner Friedman,