Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6371287 | Journal of Theoretical Biology | 2012 | 11 Pages |
Abstract
⺠The system's responses to TNFa are characterised by a supercritical Hopf bifurcation. ⺠A second oscillatory regime appears at much lower doses at certain reaction rates. ⺠The qualitative dynamics are most sensitive to the details of NF-kB mediated gene transcription.
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Authors
Yunjiao Wang, Pawel Paszek, Caroline A. Horton, Hong Yue, Michael R.H. White, Douglas B. Kell, Mark R. Muldoon, David S. Broomhead,