Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6371373 | Journal of Theoretical Biology | 2012 | 16 Pages |
Abstract
⺠Gene regulatory networks include indirect interactions between enzymes and genes. ⺠We investigate to which extent indirect interactions influence the network dynamics. ⺠We develop qualitative models of the network controlling carbon assimilation in Escherichia coli. ⺠The network dynamics is significantly different with and without indirect interactions. ⺠Only models with indirect interactions can reproduce the available experimental data.
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Authors
Valentina Baldazzi, Delphine Ropers, Johannes Geiselmann, Daniel Kahn, Hidde de Jong,