Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6371375 | Journal of Theoretical Biology | 2012 | 9 Pages |
Abstract
⺠We consider cooperation of the MAPK cascade with scaffolds. ⺠Double MEK and ERK phosphorylation enables signaling via scaffolds. ⺠Scaffolds assure high specificity of signaling at low signals. ⺠Scaffolding and double phosphorylation in MAPK cascades coevolved.
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Authors
PaweÅ Kocieniewski, James R. Faeder, Tomasz Lipniacki,