Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6371722 | Journal of Theoretical Biology | 2006 | 17 Pages |
Abstract
Recent experimental work has identified the principal components arrayed by Escherichia coli in its sensing of, and response to, varying levels of oxygen. This apparatus may be leveraged/modified by the metabolic engineer to identify nonuniform oxygen and glucose regimens that deliver better yields than their uniform counterparts. Toward this end we build and analyse a mathematical model that captures the role played by oxygen in the regulation of cytochrome production in E. coli.
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Authors
Bradford E. Peercy, Steven J. Cox, Sagit Shalel-Levanon, Ka-Yiu San, George Bennett,