On the Eulerian formulation of a stress induced platelet activation function

This paper introduces a general concept of Eulerian reformulation of Langrangian particle tracking methods in evaluation of platelet damage and activation. It is applied to formulation of a new multistage algorithm describing the delayed activation of platelets due to excessive exposure to supra-critical stress. This new class of multistage Eulerian activation models allows for numerous extensions and generalizations, while preserving its simplicity and flexibility.